What dose of red clover helps hot flashes?
A meta-analysis found a dose-dependent effect, strongest at 80mg or more per day of isoflavone extract, and in women with 5 or more flashes per day at baseline.
The short answer
A meta-analysis of 8 trials found red clover isoflavone extract produced a statistically significant, dose-dependent reduction in daily hot flash frequency, with the strongest effect at 80mg or more per day and in women experiencing 5 or more flashes daily before starting. That said, the Menopause Society has not formally endorsed red clover, so this is best understood as a modest, real complementary effect rather than a guaranteed fix. Standardized extract is meaningfully more concentrated than traditional dried-flower tea, which was historically used as a general "blood purifying" tonic before its isoflavone content was identified.